Project information
Environment - carcinogenesis - oncology
- Project Identification
- MSM 141100003
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- environmental pollutants; genotoxic agents; mechanisms of genomic and extragenomic carcinogenesis; predictive bioparameters ; optimization of oncological therapy
The aim of this multidisciplinary project is to contribute to the research of the mechanisms of carcinogenesis with a special interest devoted to reduction of risks from environmental pollutants and genotoxic effects of therapeutic agents. The investigation of effects of persistent organic pollutants and other genotoxic compounds on induction and development of malignant tumors. The special interest will be paid also to the process of extragenomic carcinogenesis. Biomathematical analysis of risks of genotoxicity in their real proportions, which couples the data from basic environmental reasearch, toxicology, experimental biology and clinical oncology. Multivariate mathematical analysis of oncological bioparameters directed mainly to prediction of the efficacy of treatment in different types of tumors and optimization of therapeutic regimens.
Publications
Total number of publications: 670
2003
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Impact of the scientific and technological development on the Chemical Weapons Convention
XV. Amaldi Conference on Problems of Global Security, year: 2003
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Implementation of the Stockholm Convention (2001) on Persistent Organic Pollutants in the Czech Republic and Czech Armed Forces
International Conference Economics, Logistics and Ecology in the Armed Forces, Brno 2003. Sborník konference, year: 2003
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In vitro inhibition of GJIC in WB-F344 cells by polar derivatives of PAHs.
SETAC Europe 13th Annual Meeting, year: 2003
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Isomer-soecific analysis of chlorinated biphenyls, naphthalenes and dibenzofurans in Delor: polychlorinated biphenyl preparations from the former Czechoslovakia
Environmental polution, year: 2003, volume: 126, edition: -
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Legal aspects of protecting air against releases of persistent organic pollutants
18th International Conference Air Protection, year: 2003
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Možná úskalí při zavádění skríningu pro včasný záchyt karcinomu prsu
J. Abrahámová (Ed) Vybrané otázky onkologie VI, year: 2003, number of pages: 3 s.
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Nádory hrtanu
Onkologická péče, year: 2003, volume: 7, edition: 2
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New generations of protective masks:Unavoidable means for protection at any CW-demil operations: Chemical Weapons
Demilitarisation Conference CWD 2003, year: 2003
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New generations of the Czechoslovak/Czech protective masks for armed forces and civil population
Symposium on nuclear, biological and chemical threats A crisis management challenge, NBC 2003, year: 2003
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New challenge of crisis management and protection of population:Chemical, biological, radiological and nuclear terrorism.
Seminář Zapojení vysokých škol do procesu přípravy a realizace koncepce v oblasti krizo obyvatelstva. FCH VUT Brno, 2003. Sborníkvého řízení a ochrany, year: 2003