Project information
Czech National Infrastructure for Biological Data
(ELIXIR-CZ)
- Project Identification
- LM2015047
- Project Period
- 1/2016 - 12/2019
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Jaroslav Koča, DrSc.
- RNDr. Petr Kulhánek, Ph.D.
- Mgr. Martin Prokop, Ph.D.
- RNDr. Tomáš Raček, Ph.D.
- RNDr. David Sehnal, Ph.D.
- doc. RNDr. Radka Svobodová, Ph.D.
- prof. RNDr. Michaela Wimmerová, Ph.D.
- Other MU Faculty/Unit
-
Institute of Computer Science
- prof. RNDr. Luděk Matyska, CSc.
- Mgr. Ivana Křenková
- Mgr. Slávek Licehammer
- RNDr. Michal Procházka, Ph.D.
- Mgr. Zdeněk Salvet
- Project Website
- https://www.elixir-czech.cz/
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. Jiří Vondrášek, CSc.
University of South Bohemia České Budějovice
Charles University
Palacký University, Olomouc
Prague Institute of Chemical Technology
St. Anne's University Hospital Brno
Biological Centre of the ASCR, v. v. i.
Institute of Biotechnology CAS
It is a current global trend that life science experiments generate an immense and steadily increasing volume of data. The Czech Republic feels this trend very strongly, because several new life science infrastructures were successfully established here, and they produce large amounts of data. It is necessary to store the data, safely manipulate with them, efficiently extract key information, etc. ELIXIR CZ is an infrastructure which is prepared to accept this challenge.
Thus, ELIXIR CZ aims to create a sustainable infrastructure for storing, processing and analysis of life science data in the Czech Republic. It will also provide tools and training that will facilitate performing these activities. Currently, ELIXIR CZ involves eleven institutions - nine life science research centres and two IT infrastructures. ELIXIR CZ also creates a communication platform for life science research institutes in the Czech Republic. ELIXIR CZ is a node of the European ESFRI project ELIXIR and is strongly involved in its activities. The ELIXIR project was approved by the Competitiveness Council from ESFRI as one of three prioritised Research Infrastructures.
Publications
Total number of publications: 68
2020
-
PDBe-KB: a community-driven resource for structural and functional annotations
Nucleic acids research, year: 2020, volume: 48, edition: D1, DOI
-
Predicting protein stability and solubility changes upon mutations: data perspective
ChemCatChem, year: 2020, volume: 12, edition: 22, DOI
-
Stereoselective Bromoboration of Acetylene with Boron Tribromide: Preparation and Cross-Coupling Reactions of (Z)-Bromovinylboronates
The Journal of Organic Chemistry, year: 2020, volume: 85, edition: 11, DOI
-
Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family
Computational and Structural Biotechnology Journal, year: 2020, volume: 18, edition: December 2020, DOI
-
Structures of hyperstable ancestral haloalkane dehalogenases show restricted conformational dynamics
Computational and Structural Biotechnology Journal, year: 2020, volume: 18, edition: 2020, DOI
-
The impact of tunnel mutations on enzymatic catalysis depends on the tunnel-substrate complementarity and the rate-limiting step
Computational and Structural Biotechnology Journal, year: 2020, volume: 18, edition: 2020, DOI
-
Visualization and Analysis of Protein Structures with LiteMol Suite
STRUCTURAL BIOINFORMATICS: METHODS AND PROTOCOLS, year: 2020, number of pages: 13 s.
2019
-
Automated family-wide annotation of secondary structure elements
Protein supersecondary structures: Methods and protocols, edition: Vyd. Second Edition, year: 2019, number of pages: 25 s.
-
Caver Web 1.0: identification of tunnels and channels in proteins and analysis of ligand transport
Nucleic acids research, year: 2019, volume: 47, edition: W1, DOI
-
CaverDock: a molecular docking-based tool to analyse ligand transport through protein tunnels and channels
Bioinformatics, year: 2019, volume: 35, edition: 23, DOI