Project information
Czech National Infrastructure for Biological Data
(ELIXIR-CZ)
- Project Identification
- LM2015047
- Project Period
- 1/2016 - 12/2019
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Jaroslav Koča, DrSc.
- RNDr. Petr Kulhánek, Ph.D.
- Mgr. Martin Prokop, Ph.D.
- RNDr. Tomáš Raček, Ph.D.
- RNDr. David Sehnal, Ph.D.
- doc. RNDr. Radka Svobodová, Ph.D.
- prof. RNDr. Michaela Wimmerová, Ph.D.
- Other MU Faculty/Unit
-
Institute of Computer Science
- prof. RNDr. Luděk Matyska, CSc.
- Mgr. Ivana Křenková
- Mgr. Slávek Licehammer
- RNDr. Michal Procházka, Ph.D.
- Mgr. Zdeněk Salvet
- Project Website
- https://www.elixir-czech.cz/
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. Jiří Vondrášek, CSc.
University of South Bohemia České Budějovice
Charles University
Palacký University, Olomouc
Prague Institute of Chemical Technology
St. Anne's University Hospital Brno
Biological Centre of the ASCR, v. v. i.
Institute of Biotechnology CAS
It is a current global trend that life science experiments generate an immense and steadily increasing volume of data. The Czech Republic feels this trend very strongly, because several new life science infrastructures were successfully established here, and they produce large amounts of data. It is necessary to store the data, safely manipulate with them, efficiently extract key information, etc. ELIXIR CZ is an infrastructure which is prepared to accept this challenge.
Thus, ELIXIR CZ aims to create a sustainable infrastructure for storing, processing and analysis of life science data in the Czech Republic. It will also provide tools and training that will facilitate performing these activities. Currently, ELIXIR CZ involves eleven institutions - nine life science research centres and two IT infrastructures. ELIXIR CZ also creates a communication platform for life science research institutes in the Czech Republic. ELIXIR CZ is a node of the European ESFRI project ELIXIR and is strongly involved in its activities. The ELIXIR project was approved by the Competitiveness Council from ESFRI as one of three prioritised Research Infrastructures.
Publications
Total number of publications: 68
2017
-
Ancestral Haloalkane Dehalogenases Show Robustness and Unique Substrate Specificity
CHEMBIOCHEM, year: 2017, volume: 18, edition: 14, DOI
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Catalytic Cycle of Haloalkane Dehalogenases Toward Unnatural Substrates Explored by Computational Modeling
JOURNAL OF CHEMICAL INFORMATION AND MODELING, year: 2017, volume: 57, edition: 8, DOI
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Computational Analysis of Protein Tunnels and Channels
PROTEIN ENGINEERING. METHODS AND PROTOCOLS, year: 2017, number of pages: 18 s.
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LiteMol suite: interactive web-based visualization of large-scale macromolecular structure data
Nature Methods, year: 2017, volume: 14, edition: 12, DOI
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Metagenome-derived Haloalkane Dehalogenases with Novel Catalytic Properties
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, year: 2017, volume: 101, edition: 16, DOI
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Structure-function Relationships and Engineering of Haloalkane Dehalogenases.
HANDBOOK OF HYDROCARBON AND LIPID MICROBIOLOGY SERIES. AEROBIC UTILIZATION OF HYDROCARBONS, OILS, AND LIPIDS, year: 2017, number of pages: 21 s.
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Watergate: Visual Exploration of Water Trajectories in Protein Dynamics
Eurographics Workshop on Visual Computing for Biology and Medicine, year: 2017
2016
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HotSpot Wizard 2.0: Automated Design of Site-Specific Mutations and Smart Libraries in Protein Engineering
Nucleic Acids Research, year: 2016, volume: 44, edition: W1, DOI