Project information
The yeast cell wall as an extracellular matrix: cytoskeleton and cell wall functions
- Project Identification
- GA204/00/0394
- Project Period
- 1/2000 - 1/2002
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Medicine
In terms of origin, chemical composition and structure, the cell wall can be regarded as an extracellular matrix, but evidence of its structural and functional relation to the cytoplasm is still missing. The objective of the project is to elucidate relat ionships between cytoskeletal components (actin and tubulin) and the cell wall during its growth, de novo formation, in the period of increased turnover, i.e., during cell vegetative growth, at mating, at sporulation and during protoplast regeneration. T he project will also include investigations into links between the cytoplasm and cell wall by means of transmembrane proteins of integrin type, into molecular linkers between the cytoskeleton and transmembrane proteins and into interactions between these proteins and cell wall polymers. The microorganisms used as models will be the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe in various phases of the cell cycle, the protoplasts of these species during regenerati
Publications
Total number of publications: 17
2000
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Characterization of a fission yeast mutant which displays defects in cell wall integrity and cytokinesis
Tenth International Symposium on Yeasts The rising power of yeasts in science and industry, year: 2000
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Odpověď kvasinkových buněk na teplotní šok: vliv osmotického, radiačního a mírného teplotního šoku
Tomáškovy dny 2000, year: 2000
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Osmotic shock affects cell wall and cytoskeleton in Saccharomyces cerevisiae
Cellular and Molecular Biology, year: 2000, volume: 46, edition: -
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Reakce cytoskeletu a buněčné stěny kvasinek na osmotický šok
Sborník VIII. Cytoskeletálního klubu, year: 2000
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Stability of yeast cytoskeleton under cell stress
Folia Microbiologica, year: 2000, volume: 45, edition: 1
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Studium cps mutant Schizosaccharomyces pombe
XXVIII. výročná konferencia o kvasinkách, year: 2000
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Study of cps mutants of Schizosaccharomyces pombe
Folia Microbiologica, year: 2000, volume: 45, edition: 1